Search on: TYPE II SECRETION SYSTEMS 
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Descriptor English:   Type II Secretion Systems 
Descriptor Spanish:   Sistemas de Secreción Tipo II 
Descriptor Portuguese:   Sistemas de Secreção Tipo II 
Synonyms English:   Bacterial Secretion System, Type II
T2SS Secretion System
Type 2 Secretion System
Type 2 Secretion Systems
Type II Secretion System
Secretion System, T2SS
System, T2SS Secretion  
Tree Number:   D05.500.890.500.750
Definition English:   Gram-negative bacterial secretion systems which carry out the secretion of folded proteins.T2SSs secrete folded proteins from the PERIPLASMIC SPACE that have been exported there by SEC TRANSLOCASE or TAT SECRETION SYSTEMS, or they secrete folded proteins directly from the CYTOPLASM. The T2SSs have four substructures, an ATPase, an inner membrane platform, a pseudopilin, and secretin, an outer membrane complex which is a channel for secretion. (This bacterial secretin is not the same as the mammalian hormone also named SECRETIN.) 
History Note English:   2016 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55946 
Unique Identifier:   D000069178 

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